Easy access to validated biomaterials removes resource barriers for researchers currently working on CMT4B3/SBF1/MTMR5 and for others new to the field.

We recognize that CMT4B3 therapeutic development is dependent on the research scientists’ unobstructed access to quality-controlled research tools and we are continually developing methods, tools, and other resources for all researchers working on CMT4B3/SBF1/MTMR5.

Our goal is to broaden the participation of the CMT4B3 research community by providing ever sharper tools for understanding the disease and for developing effective therapies. Easier access should also help accelerate research and increase the participation of the CMT4B3 research community.

Generating iPSC Lines & Edited iPSC Lines

Infinity Biologix (IBX), Piscataway, New Jersey

We have teamed with a Biobank, Infinity Biologix, to generate iPSC lines and edited (corrected) iPSC lines to use as a freely available resource for our research team, and anyone who wants to research CMT4B3. iPSC’s are derived from skin or blood cells that have been reprogrammed back into an embryonic-like pluripotent state that enables the development of an unlimited source of any type of human cell needed for research purposes. iPSC’s are extremely valuable research tools used for testing drugs and learning more about disease mechanisms. An edited iPSC line takes the mutated cells and genetically engineers them using CRISPR technology to correct the genetic mutations. 

As a leading next-generation central laboratory with over 21 years’ experience, Infinity BiologiX (IBX) has optimum scientific, project management and regulatory expertise. IBX provides a comprehensive physical and digital chain of custody for the collection, processing, analytics and biobanking of samples for all cellular and multi omics-based research. IBX has specific knowledge of the latest bioanalytical platforms to minimize the biomaterials needed, leverage cost efficiencies, improve data quality and reduce timelines for completion.

Frequently Asked Questions

HOW CAN I OBTAIN CMT4B3 BIOMATERIALS?

Please email info@cmt4b3research.org for biomedical data requests.
Approved IRB requests will be accommodated after completing an MTA.

DOES CMT4B3 GIVE ACCESS TO MATERIALS, ANIMALS, OR SPECIAL SERVICES?

Hunters CMT4B3 Research Foundation can make certain materials—such as cell lines, animal models—available depending on the project.

I HAVE A SUGGESTION FOR A REAGENT THAT WOULD BE IMPORTANT TO THE CMT4B3 RESEARCH COMMUNITY, WHO DO I CONTACT TO DISCUSS?

We continuously seek out and commission biological reagents that may be useful to CMT4B3 researchers. Please forward your suggestions to info@cmt4b3research.org